Dr. Holger Stephan obtained a Diploma in Chemistry from the Technical University Bergakademie Freiberg in 1981 and a PhD in organic chemistry at the same University in 1989 with Prof Jörg Beger (thesis work: amido podands – synthesis and investigations of solvent extraction of metal salts). He was the head of a working group (Centre of Research and Technology of Microelectronics Dresden, 1981-1984), assistant research scientist (Technical University Bergakademie Freiberg/Company of Synthetic Fibres Schwarza, 1984 – 1989), research fellow (Central Institute of Solid State Physics and Material Research Dresden, 1989-1993), Senior scientist (Technical University Dresden, Institute of Inorganic Chemistry, 1994-1997) then research fellow (Forschungszentrum Dresden-Rossendorf) since 1998. He’s the Spokesperson of the Helmholtz Virtual Institute "Functional nanomaterials for multimodality cancer imaging (NanoTracking)"(www.hzdr.de/Nanotracking). His research areas are : Development and characterization of new radiotracer and extractants, Supramolecular Chemistry, Dendrimer Chemistry, Coordination Chemistry and Thermodynamics of Liquid Two-phase Systems.

Dr. Holdger's research group has comprehensive experiences for undertaking radiotracer experiments, different spectroscopic techniques, characterization of colloid-chemical properties and in vitro/in vivo studies in view of the development and characterization of novel radiotracers, including functionalized nanoparticles. The design and development of chemically, metabolically and radiolytically stable radiometal complexes on the basis of 64Cu/67Cu is of special interest. Furthermore, polynuclear metal compounds (polyoxometalates, Re clusters) for anti-tumor activity, photosensitizing, and radiation-sensitizing properties are under investigation. The characterization of binding and transport behavior of novel receptors by solvent extraction studies represents one main topic.