Claire Wilhelm, biophysicist, has oriented her research to the biomedical field since obtaining her PhD in 2003 in soft matter physics. This last decade, she used her knowledge of materials science to advance the field of nanomedicine, by adopting the materials angle from the outset. The goal has been to provide the fullest possible picture of the modes of action and fates of magnetic nanoparticles in their biological target environments. In doing so, she has worked mostly (i) in biophysics and (ii) in physical chemistry interfacing with therapy. The former has been awarded an ERC consolidator grant in 2014 (MaTissE) and led to the development of magnetic-based methods to manipulate living cells, explore tissue mechanics, and provide magnetic artificial tissue replacements. The latter has also been awarded an ERC consolidator grant in 2019 (NanoBioMade). It was founded on previous works proposing combined cancer solutions by applying multiple stimuli to the same nanoparticle, introducing the use of magnetic nanoparticles as photothermal tools, and developing extracellular vesicles engineering with nanoparticles and drugs as bio-camouflaged vectors. Claire Wilhelm received the CNRS bronze medal in 2011, the Louis Ancel prize in 2014, the CNRS silver medal in 2022, and the chemistry medal from Académie des Sciences in 2024. She has co-authored 210+ publications (22 000+ citations, h-index 76), 9 patents, and she delivered 70+ invited lectures