Prof. Aleksandra Radenovic
Prof Aleksandra Radenovic is Associate Professor since 2015. She had her PhD under the supervision of Prof. Dietler in Laboratory of Physics of Living Matter, University of Lausanne- Switzerland. She then joined the group of Prof.Liphardt at the University of California, Berkeley- USA for three years as a post-doctoral researcher. She got in 2008 a
Tenure-Track Assistant Professor position.
Her lab works in the research field that can be termed single molecule biophysics. they develop techniques and methodologies based on optical imaging, biosensing and single molecule manipulation with the aim to monitor the behavior of individual biological molecules and complexes in vitro and in live cells. Their current research is focused on three major directions:
(i) Developing and using nanopores as platform for molecular sensing and manipulation. In particular we focus on solid-state nanopores realized either in glass nanocapillaries, or on suspended 2d-material membranes and standard silicon-nitride membranes.
(ii) Studying how biomolecules function, especially how proteins and nucleic acids interact, using force-based manipulation single-molecule techniques, in particular optical tweezers, optical wrench system, Anti- Brownian Electrokinetic (ABEL) trap and combination of nanopore/nanocapillaries with OT.
(iii) Developing super-resolution optical microscopy, based on single molecule localizations (SMLM) in cells with molecular-scale resolution, with an aim to extract quantitative information.